What is the most sensitive criteria when ruling in melanoma?

The most sensitive criterion when ruling in melanoma is the evolution of the lesion. This refers to any changes that occur in a mole or skin lesion over time, including alterations in size, shape, color, or elevation, as well as developing new symptoms such as itching or bleeding. The principle behind this criterion is that melanoma often presents with significant changes that differentiate it from benign skin conditions.

In clinical practice, a lesion that has evolved over time raises suspicion for malignancy, highlighting the importance of careful monitoring for any shifts from its original characteristics. While individual changes such as a color change or increase in size can be significant, evolution encapsulates a broader range of changes, making it a more powerful predictor of melanoma. Therefore, the detection of any alteration is critical for early diagnosis and treatment. The initial appearance of a lesion is important for baseline assessment; however, the evolution of a lesion provides essential insight into its potential malignancy status.