During an eye examination, what does a red reflex in one eye and a white reflex in the other indicate?

A red reflex in one eye and a white reflex in the other is an unexpected finding during an eye examination. The red reflex is produced by light reflecting off the retina, and it is typically observed in both eyes when a light source is directed at them. The presence of a red reflex indicates that the optical media—cornea, lens, and vitreous humor—are clear, which is crucial for healthy vision.

In contrast, a white reflex (also known as leukocoria) noted in one eye suggests potential underlying issues such as retinoblastoma, cataract, or other abnormalities in the eye. Such findings require further investigation to diagnose the underlying condition accurately. Noting a difference in reflex color between the two eyes is critical, as it may indicate a pathological condition that needs prompt assessment and intervention. Recognizing this discrepancy emphasizes the importance of thorough eye examinations, particularly in pediatric assessments.